| 090026 |
Turkey |
THE DESIGN OF MICROFLUIDIC PUMP (MFP) FOR MEDICAL FIELD |
IZMIR PRIVATE CAKABEY SCHOOLS |
Sila Karakusoglu
Lara Yucebas |
The ability of microfluidic (MF) device technologies to provide a lot of information with a small amount of sample, the opportunities it provides increases their use in the medical field in the bedside monitoring in drug delivery systems. Three-dimensional (3D) printer technologies provide advantages such as cost-effectiveness in the production of MF devices and quick and easy production in complex designs. In our project, it is aimed to design microfluidic pumps (MFP) to be used in medical field and conduct its production with 3D printer technologies. The developed MFP is intended to be at low cost, bio-compatible, adaptable and portable to the drug, suitable flow properties as a pharmaceutical pump. First of all, MFP air channel, flow channel parts were designed and printed with the help of 3D printer, on AutoCAD, one of the professional drawing programs. The poly(dimethylsiloxane) (PDMS) membrane that will enable MFP activation is produced in different thicknesses and glued to the air channel of MFP, and the resistance to the applied pressure is observed and the appropriate membrane thickness is determined as ~ 235μm. Liquid PDMS was applied to the inner surfaces of MFP's air and flow channel, PDMS membrane was placed between them and the parts were assembled in the oven at 60ºC. MFP has been connected to the pneumatic valve system, where operation codes have been prepared with Arduino Uno, and flow properties have been examined. The flow rate of MFP is ~ 50 μL/min at a maximum of 15 Hz and the backpressure is ~ 0.085 Pa under maximum pressure of 3 bar. In addition, values such as size, membrane thickness and applied pressure for the possible models of MFP were supported by theoretical calculations. As a result, MFP which is biocompatible, drug adaptable, portable, wearable technology applications potential and has suitable flow characteristics as a pharmaceutical pump has been developed. MFP introduced a microfluidic pump system which can make life easier for the patient and contribute to the national economy through domestic production and can be used as a drug pump in the treatment of diseases such as diabetes and cancer.
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| 090027 |
Iran |
Fabrication and Characterization of Biological Electrospinning Nanofiber Scaffold Based on Cellulose Diacetate-Gelatin-Green Tea for Tissue Engineering Applications |
Avicenna research center |
Zohre Mahdavi Sabet |
Recently, tissue engineering technology has developed modern therapies such as the production of wound dressings, bio-pads, scaffolds, and dressings with the goal of reducing the effects of deep and extensive skin wounds. In this project, in order to increase wound healing using nanotechnology, we produced electrospun nanofibers scaffolds based on biodegradable materials such as gelatin (which is a natural and hydrophilic polymer), and cellulose diacetate (which has the optimal biodegradability). Also, we used green tea extract to improve the biological properties of scaffolds such as anti-oxidant and anti-bacterial properties. In this regard two syringes include a polymeric solution of gelatin in acetic acid and a polymeric solution of the mixture of cellulose di-acetate in acetone and green tea extract, respectively, were attached to separate feed pumps, then hybrid nanofibrous webs were produced using the co-electrospinning method. SEM images showed that the Synthesized scaffold had the finesse and uniformity structure for simulation of extracellular matrix. As well as, the contact angle of the water droplet and the web surface indicated that the hydrophilicity of this scaffold is optimal and it can control the degradability and cell adhesion. According to the results of the antimicrobial test, the nanofibrous scaffold with green tea extract has antibacterial properties against E-coli and S-aureus bacteria. The results of the evaluation of the cell morphology on nanofibrous scaffolds indicate the appropriate adhesion and expansion of the fibroblasts on the scaffold, which confirms the biocompatibility of the tissue-engineered scaffolds.
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| 090028 |
Russia |
Development of a neurointerface glove with tactile feedback |
Lomonosov Moscow State University Gymnasium |
Mariia Lapchinskaia
Artem Ovchinnikov
Olga Piskunova |
The aim of the project was to create a simulator for fine motor skills of the hand based on a brain-computer interface coupled with a physical hand phantom for patients after neurotrauma and stroke. The relevance of the project is due to the fact that stroke continues to be one of the most important medical and social problems [1]. The ineffectiveness of already existing methods of rehabilitation demonstrates the need to develop new methods of rehabilitation. The most promising is the improvement of the brain-computer interface technology, which isn’t used in a daily practice, but its effectiveness has already been proven [2]. For this reason, the creation of a simulator for the recovery of patients is a necessity, which will not only increase the number of successful recoveries of patients, but also reduce the workload on the medical staff. Key words: hybrid brain computer interfaces, neurorehabilitation, P300, motor imagery References: 1. Manvelov L., Kadykov A. (2002). Stroke is a social and medical problem. Science and life, 5. 2. Kaplan A.I. et al (2013). Experimental and theoretical foundations and practical implementations of the "brain-computer interface" technology. From science to practice new technologies, pp 21-29.
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